Kinetics of Exogenous Induction of the Hexose-6-Phosphate Transport System of Escherichia coli

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Compartmentation in the induction of the hexose-6-phosphate transport system of Escherichia coli.

The induction of the hexose-6-phosphate transport system was investigated. Glucose-6-phosphate (G6P) at concentrations as low as 10(-4)m was able to induce this system in wild-type cells, as well as in mutants lacking phosphoglucose isomerase or G6P dehydrogenase. Growth in the presence of fructose-6-phosphate (F6P) induced the system only if the cells contained phosphoglucose isomerase. Furthe...

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Studies on the uptake of hexose phosphates. II. The induction of the glucose 6-phosphate transport system by exogenous but not by endogenously formed glucose 6-phosphate.

An Escherichia coli mutant, DF2000, accumulates up to 0.06 M glucose 6-phosphate when supplied glucose. This extremely large concentration of intracellular glucose 6-phosphate does not serve to induce the active transport of this ester. However, if the medium is then supplemented with only 5 X 1O-4 M glucose 6-phosphate the transport system is induced. Thus, it appears that exogenous glucose 6-...

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Role of the phosphotransferase system in Escherichia coli strains deficient in hexose phosphate transport.

In Escherichia coli, glucose 6-phosphate is transported via the Uhp system which is inducible by glucose 6-phosphate. We showed that, in a uhp-deficient strain, glucose 6-phosphate was dephosphorylated in the periplasm and that the resulting glucose was subsequently transported into the cells via the phosphotransferase system. The uptake of glucose generated from glucose 6-phosphate allowed the...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1971

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.107.1.74-78.1971